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姓名：邰发道 |
职称/职务：教授 |
电话：029-85310286 |
传真： |
电子信箱：taifadao@snnu.edu.cn; taifadao@yahoo.com |
研究方向：动物行为学行为生理学 |
办公地点：格物楼3341 |
一、个人简介
1990-1993年金沙1005cc登录网址是多少生物系学习，并获得硕士学位，同年7月参加工作，主要从事动物学、动物生态学、动物行为学、生理生态学、行为神经生物学教学和研究工作。1999年获得动物学博士学位。2000-2002年在著名生态学家孙儒泳院士的指导下开展博士后研究工作。2003年聘为js33333金沙线路检测教授，2004年聘为博士生导师，2006年至2007年在瑞典卡若林斯卡医学院神经科学系作访问学者。2016年至2017年在美国莱特州立大学做高级研究学者。主持八项国家自然科学基金和五项陕西省和教育部课题，在国内外学术刊物上发表论文100余篇。
二、主要研究领域及兴趣
1.动物社会行为发生的行为神经内分泌机制
2.动物社会行为的适应与进化
3.内分泌干扰物对行为和神经内分泌的影响
三、承担的科研项目
1.主持国家自然科学基金面上项目，田鼠对嗅觉信息的识别和记忆及其神经生物学机制，2003.1.1-2005.12.31, 30200026
2.主持国家自然科学基金面上项目，不同婚配制度田鼠社会行为发育形成的行为神经内分泌机制，2007.1.1-2009.12.31, 30670273
3.主持国家自然科学基金面上项目，基因和早期社会环境相互作用对田鼠配偶关系和社会联系表达的调控，2010.1.1-2012.12.31, 30970370
4.主持国家自然科学基金面上项目，首届亚太地区整合行为科学国际会议，2011.7.1-2011.9.31, 31110303029
5.主持国家自然科学基金面上项目，早期社会生态因素对棕色田鼠同伴亲密行为和神经内分泌特征的影响及其调控机制，2012.1.1-2015.12.31, 31170377
6.主持国家自然科学基金面上项目，棕色田鼠父本行为的神经机制研究，2013.1.1-2017.12.31, 31372213
7.主持国家自然科学基金面上项目，社会应激对亲社会行为的影响及其神经内分泌机制，2017.1.1-2020.12.31， 31670421
8.主持国家自然科学基金面上项目，社会环境对共情行为的影响及其神经内分泌机制。2020.1.1-2013.12.31， 31970424
9.主持教育部高等学校博士点专项科研基金项目，基于田鼠为动物模型的异常社会行为发生的行为神经内分泌机制研究，2007.1.1-2009.12.31，20060718003
10.主持教育部科学技术重点项目，2003－2005棕色田鼠繁殖调控及抗生育技术研究，2003.1.1-2005.12.31，103149
11.主持陕西省自然科学基金项目，基于田鼠为动物模型的同性恋发生的神经内分泌机制研究，2008.1.1-2011.12.31，SJ08C103
12.主持中央高校科研业务费项目，焦虑抑郁行为发生的神经机制及调节，2010.1.1-2012.12.31，GK200901011
四、代表性论文
1. Li, LF; Yuan, W ; He, ZX ; Ma, H ; Xun, YF ; Meng, LR ; Zhu, SJ ; Wang, LM ; Zhang, J; Cai, WQ ; Zhang, XN; Guo, QQ ; Lian, ZM ; Jia, R ; Tai, FD.2020. Reduced Consolation Behaviors in Physically Stressed Mandarin Voles: Involvement of Oxytocin, Dopamine D2, and Serotonin 1A Receptors Within the Anterior Cingulate Cortex. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY. 23: 511-523
2. Guo, QQ ; Wang, LM ; Yuan, W ; Li, LF; Zhang, J ; Hou, WJ ; Yang, Y ; Zhang, XN ; Cai, WQ; Ma, H ; Xun, YF ; Jia, R ; He, ZX ; Tai, FD.2020. Different effects of chronic social defeat on social behavior and the brain CRF system in adult male C57 mice with different susceptibilities. BEHAVIOURAL BRAIN RESEARCH, 384: 112553
3. Hou, WJ ; He, ZX ; Yang, Y ; Yuan, W] ; Wang, LM ; Zhang, J ; Zhang, XN ; Cai, WQ ; Guo, QQ ; Tai, FD.2020. The involvement of oxytocin in the effects of chronic social defeat stress on emotional behaviours in adult female mandarin voles. EUROPEAN JOURNAL OF NEUROSCIENCE,52: 2853-2872
4. Yuan, W ] ; Li, LF; Hou, WJ ; He, ZX ; Wang, LM; Zhang, J ; Yang, Y; Cai, WQ ; Guo, QQ ; Zhang, XN; Jia, R ; Lian, ZM ; Tai, FD. 2020.Preweaning Paternal Deprivation Impacts Parental Responses to Pups and Alters the Serum Oxytocin and Corticosterone Levels and Oxytocin Receptor, Vasopressin 1A Receptor, Oestrogen Receptor, Dopamine Type I Receptor, Dopamine Type II Receptor Levels in Relevant Brain Regions in Adult Mandarin Voles. NEUROENDOCRINOLOGY, 110: 292-306
5. He, ZX； Young, L ; Ma, XM ; Guo, QQ ; Wang, LM ; Yang, Y ; Luo, L ; Yuan, W ; Li, LF; Zhang, J ; Hou, WJ ; Qiao, H; Jia, R; Tai, FD. 2019] Increased anxiety and decreased sociability induced by paternal deprivation involve the PVN-PrL OTergic pathway. ELIFE, 8: e44026
6. Wang, LM ; He, ZX ; Zhu, ZX ; Yuan, W ; Cai, WQ ; Li, LF ; Zhang, J ; Hou, WJ; Yang, Y; Zhang, XN; Guo, QQ ; Wang, X ; Lian, ZM ; Tai, FD.2019.The serotonin system in the hippocampus CA3 involves in effects of CSDS on social recognition in adult female mandarin voles (Microtus mandarinus). PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY95
7. Hennessy, MB ; Tai, FD ; Carter, KA ; Watanasriyakul, WT ; Gallimore, DM; Molina, AL; Schiml, PA .2019. Central oxytocin alters cortisol and behavioral responses of guinea pig pups during isolation in a novel environment. PHYSIOLOGY & BEHAVIOR. 212
8. Feng, T; An, SC ; Kinden, R ; Zhang, X; Jia, R ; Tai, FD.2019. Alteration in oxytocin levels induced by early social environment affects maternal behavior and estrogen receptor alpha in mandarin voles (Microtus mandarinus). BEHAVIOURAL BRAIN RESEARCH365: 36-47.
9. Yuan, W; He, ZX ; Hou, WJ ; Wang, LM ; Li, LF ; Zhang, J ; Yang, Y ; Jia, R ; Qiao, H ; Tai, FD . 2019. Role of oxytocin in the medial preoptic area (MPOA) in the modulation of paternal behavior in mandarin vole. HORMONES AND BEHAVIOR, 110: 46-55
10. Wang, LM; Zhu, ZX ; Hou, WJ; Zhang, XN; He, ZX ; Yuan, W ; Yang, Y ; Zhang, SY ; Jia, R ; Tai, FD.2019. Serotonin Signaling Trough Prelimbic 5-HT1A Receptors Modulates CSDS-Induced Behavioral Changes in Adult Female Voles. INTERNATIONAL JOURNAL OF EUROPSYCHOPHARMACOLOGY. 22: 208-220
11. Zhang, J; He, ZX ; Wang, LM ; Yuan, W ; Li, LF ; Hou, WJ ; Yang, Y ; Guo, QQ ; Zhang, XN ; Cai, WQ ; An, SC; Tai, FD.2019. Voluntary Wheel Running Reverses Deficits in Social Behavior Induced by Chronic Social Defeat Stress in Mice: Involvement of the Dopamine System. FRONTIERS IN NEUROSCIENCE, 13: 256
12. Li, LF ; Yuan, W ; He, ZX ; Wang, LM ; Jing, XY ; Zhang, J ; Yang, Y Guo, QQ ; Zhang, XN ; Cai, WQ ; Hou, WJ ; Jia, R ; Tai, FD. 2019. Involvement of oxytocin and GABA in consolation behavior elicited by socially defeated individuals in mandarin voles. PSYCHONEUROENDOCRINOLOGY. 103: 14-24
13. He, ZX ; Guo, QQ ; Yang, Y ; Wang, LM ; Zhang, SY ; Yuan, W ; Li, LF ; Zhang, J ; Hou, WJ ; Yang, JF ; Jia, R ; Tai, FD .2018. Pre-weaning paternal deprivation impairs social recognition and alters hippocampal neurogenesis and spine density in adult mandarin voles. NEUROBIOLOGY OF LEARNING AND MEMORY, 155: 452-462
14. Wang, LM ; Hou, WJ; He, ZX ] ; Yuan, W; Yang, JF ; Yang, Y ; Jia, R ; Zhu, ZX ; Zhou, Y ; Tai, FD . 2018. Effects of chronic social defeat on social behaviors in adult female mandarin voles (Microtus mandarinus): Involvement of the oxytocin system in the nucleus accumbens. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY. 82: 278-288
15. Yuan, W; Yang, XP ; Yu, P ; Jia, R; Tai, FD ; Wei, B ; Liu, X ; Ma, LG .2018 .Different behavioral ,neural and neuropeptide responses to their own and to alien pups in mandarin voles.JOURNAL OF COMPARATIVE PHYSIOLOGY A-NEUROETHOLOGY SENSORY NEURAL AND BEHAVIORAL PHYSIOLOGY. 204: 257-269
16. Wang, B; Wang, L; Wang, K ; Tai, FD. 2018. The effects of fathering experience on paternal behaviors and levels of central expression of oxytocin and dopamine-2 type receptors in mandarin voles. PHYSIOLOGY & BEHAVIOR, 193: 35-42
17. Wu, RY ; Song, ZZ ; Tai, FD .2018. Parent-offspring cohabitation after weaning inhibits partner preference and alters central oxytocin and dopamine systems in adult mandarin vole. JOURNAL OF COMPARATIVE PHYSIOLOGY A-NEUROETHOLOGY SENSORY NEURAL AND BEHAVIORAL PHYSIOLOGY, 204: 593-604
18. Wang, B ; Li, LF ; He, ZX ; Wang, LM ; Zhang, SY ; Qiao, H; Jia, R; Tai, FD. 2018. Effects of reproductive experience on paternal behavior, levels of testosterone, prolactin in serum and dendritic spines in medial prefrontal cortex of mandarin voles. INTEGRATIVE ZOOLOGY, 13: 711-722
19. He, ZX ; Hou, WJ ; Hao, X ; Dong, N ; Du, PR ; Yuan, W ; Yang, JF ; Jia, R ; Tai, FD.2017.Oxytocin receptor antagonist treatments alter levels of attachment to mothers and central dopamine activity in pre-weaning mandarin vole pups. PSYCHONEUROENDOCRINOLOGY. 84: 124-134
20. Dong, N ; Du, PR ; Hao, X ] ; He, ZX ; Hou, WJ ; Wang, LM ; Yuan, W ; Yang, JF ; Jia, R ; Tai, FD. 2017. Involvement of GABAA receptors in the regulation of social preference and emotional behaviors by oxytocin in the central amygdala of female mandarin voles. NEUROPEPTIDES, 66:8-17
21. Du, PR ; He, ZX ; Cai, ZL ; Hao, X ; Dong, N ; Yuan, W ; Hou, WJ ; Yang, JF ; Jia, R ; Tai, FD. 2017. Chronic central oxytocin infusion impairs sociability in mandarin voles. PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR. 161: 38-46
22. Fang Q Q, Wang J L & Tai F D. 2017. Effects of cocaine on aggression and associated central ERα and oxytocin expression in ovariectomized and intact mandarin voles.Italian Journal of Zoology. 2017, 84: 116–127
23. He ZX; Zhang SW; Yu CJ; Tai FD.2017. Emotional attachment of pre-weaning pups to mothers and fathers in mandarin voles. BEHAVIOURAL PROCESSES, 135: 87-94.
24. Shen CM; Wang HD; Feng ZQ; Zhu BF;Tai FD.2017. Forensic effectiveness and population differentiations study of AGCU 21+1 fluorescence multiplex in Chinese Henan Han population. Forensic science international. Genetics. 28：18-21.
25. Zhang SW; Yu CJ; Feng T; Tai FD. 2016. The effects of olfactory and sound signals from dams during prior brief isolation on levels of paternal behaviours in mandarin voles. BEHAVIOUR, 153: 209-226
26. Li Y; Song ZY; Ding YJ; Tai FD. 2016. Effects of formaldehyde exposure on anxiety-like and depression-like behavior, cognition, central levels of glucocorticoid receptor and tyrosine hydroxylase in mice. CHEMOSPHERE,144: 2004-2012
27. Yu CJ, Zhang S W, Tai FD.2016. Effects of nucleus accumbens oxytocin and its antagonist on social approach behavior. Behavioural Pharmacology. 27:672–680
28. Wu RY; Shui L; Wang SY; Tai FD. 2016. Bilobalide alleviates depression-like behavior and cognitive deficit induced by chronic unpredictable mild stress in mice.BEHAVIOURAL PHARMACOLOGY, 27(7): 596-605
29. Li YN; Lian ZM; Wang B; Tai FD. Natural variation in paternal behavior is associated with central estrogen receptor alpha and oxytocin levels.2016. JOURNAL OF COMPARATIVE PHYSIOLOGY A-NEUROETHOLOGY SENSORY NEURAL AND BEHAVIORAL PHYSIOLOGY，139: 89-96
30. Kong LZ, Wu RY, Wang L, Feng WG, Cao Y, Tai FD.2015. Postpartum repeated separation from pups affects the behavior and neuroendocrine parameters of mandarin vole fathers. Physiology & Behavior, 139：89-96
31. Wang B, Li YN, Wu RY, Zhang SW, Tai FD.2015 Behavioral responses to pups in males with different reproductive experiences are associated with changes in central OT, TH and OTR, D1R, D2R mRNA expression in mandarin voles. Hormones and Behavior, 67, 73-82
32. Yu P, Zhang H, Li XB, He FQ, Tai FD. 2015. Early bi-parental separation or neonatal paternal deprivation in mandarin voles reduces adult offspring paternal behavior and alters serum corticosterone levels and neurochemistry. Hormones and Behavior, 73: 8-14
33. Yu CJ, Fang QQ, Tai FD. 2015. Pubertal BPA exposure changes ER levels in female mice. Environment Toxicology and Pharmacology,40:606-6714
34. Wu RY, Song ZZ, Wang S, Shui L,Tai FD, Qiao XF, He FQ, 2014, Early paternal deprivation alters levels of hippocampal brain-derived neurotrophic factor and glucocorticoid receptor and serum corticosterone and adrenocorticotropin in a sex-specific way in socially monogamous mandarin vole. Neuroendocrinology, 100,119-128
35. Wang L,Wei B, Wu RY, Kong LZ, Feng WG, Cao Y, Tai FD,Zhang X,2014,Neuroendocrine response to social isolation and paternal deprivation at different postnatal ages in mandarin voles. Developmental Psychobiology,56,1214-1228
36. Qiao XF, Yan YT, Tai FD, Wu RY, Hao P, Fang QQ, Zhang SW. 2014. Levels of central oxytocin and glucocorticoid receptor and serum adrenocorticotropic hormone and corticosterone in mandarin voles with different levels of sociability. Behavioural Brain Research, 274, 226-234
37. Qiao XF, Yan YT, Wu RY, Tai FD, Hao P, Cao Y, Wang JL. 2014. Sociality and oxytocin and vasopressin in the brain of male and female dominant and subordinate mandarin voles. Journal of Comparative Physiology A, 200,149-159
38. Cao Y., Wu R.Y., Tai E.D., Zhang X., Yu P., An X.L., Qiao X.F., Hao P.2014. Neonatal paternal deprivation impairs social recognition and alters levels of oxytocin and estrogen receptor α mRNA expression in the MeA and NAcc, and serum oxytocin in mandarin voles. Hormones and Behavior, 65(1), 57-65
39. Yu, P., An, S.C., Tai, F.D., Wang JL, Wu R.Y., Wang B.2013. Early social deprivation impairs pair bonding and alters serum corticosterone and the NAcc dopamine system in mandarin voles. Psychoneuroendocrinology, 38(12), 3128-3138
40. Wu RY, Song ZZ, Tai FD, An XL, Yu P, Li YN. 2013. The effect of alloparental experience and care on anxiety-like, social and parental behaviour in adult mandarin voles. Animal Behaviour, 85(1): 61-69
41. Yu CJ, Tai FD, Zeng SY, Zhang X. 2013. Effects of perinatal daidzein exposure on subsequent behavior and central estrogen receptor α expression in the adult male mouse. Progress in Neuro-Psychopharmacology and Biological Psychiatry, 43:157-167
42. Wei B, Tai FD, Liu X, Ma LG, Yang XP, Jia R, Zhang X. 2013.Neonatal tactile stimulation alleviates the negative effects of neonatal isolation on novel object recognition, sociability and neuroendocrine levels in male adult mandarin voles (Microtus mandarinus).Physiology & Behavior, 112-113:14-22
43. Liu X, Wu RY, Tai FD, Ma LG, Wei B, Yang XP, Zhang X, Jia R. 2013. Effects of group housing on stress induced emotional and neuroendocrine alterations. Brain Research,1502:71-80
44. Yu P, An SC, Tai FD, Zhang X, He FQ, Wang JL, An XL, Wu RY. 2012. The effects of neonatal paternal deprivation on pair bonding, NAcc dopamine receptor mRNA expression and serum corticosterone in mandarin voles. Hormones and Behavior, 61(5):669-677
45. Wang JL, Tai FD, Yu P, Wu RY. 2012. Reinforcing properties of pups versus cocaine for fathers and associated central expression of Fos and tyrosine hydroxylase in mandarin voles (Microtus mandarinus). Behavioural Brain Research, 230(1): 149-157
46. Wang JL, Tai FD, 2012. Effects of different periods of postweaning separation on father-son interaction and recognition in mandarin voles. Ethology Ecology and Evolution.24(2):117-126
47. Wang JL, Wang HC,Tai FD. 2012. Effects of Tripterygium wilfordii multiglycosides on sex hormones and receptors in mandarin vole Leydig cells. Animal Biology 62 (2012) 217–229
48. He FQ, Tai FD, Zhang YH, Zhang X, 2012. The relationship between aggressive behavior and serum sex hormone levels and sex hormone receptor in the aggression-related brain regions in the different period castrated mandarin voles. J Comp Physiol A, 198(5):347-362
49. Wang JL,Tai FD, 2012. Cocaine-induced rewarding properties, behavioral sensitization and alteration in social behaviors in group-housed and post-puberty isolated female mandarin voles. Behavioral Pharmacology, 23(7):693-702
50. Yu P, Wang JL, Tai FD, Broders H, An SC, Zhang X, He FQ, An XL, Wu RY. 2011. The effects of repeated early deprivation on ultrasonic vocalizations and ontogenetic development in mandarin vole pups. Behavioural Processes, 88(3): 162-167
51. Jia R, Tai FD, An SC, Zhang X.2011. Neonatal paternal deprivation or early deprivation reduces adult parental behavior and central estrogen receptor α expression in mandarin voles (Microtus mandarinus). Behavioural Brain Research, 224(2):279-289
52. Yu CJ, Tai FD, Song ZZ, Wu RY, Zhang X, He FQ. 2011. Pubertal exposure to bisphenol A disrupts behavior in adult C57BL/6J mice. Environ Toxicol Phar, 31(1): 88-99
53. Wu RY, Yuan AF, Yuan QW, Guo R, Tai FD, Song ZZ,Yu CJ. 2011. Comparison of sociability, parental care and central estrogen receptor alpha expression between two populations of mandarin voles (Microtus mandarinus). J Comp Physiol A, 197: 267-277
54. Guo R, Liang N, Tai FD, Wu RY, Chang G, He FQi, Yuan QW. 2011. Differences in Spatial Learning and Memory for Male and Female Mandarin Voles (Microtus mandarinus) and BALB/c Mice. Zool Stud, 50(1): 24-30
55. An XL, Zou JX, Wu RY, Yang Y, Tai FD, Zeng SY, Jia R, Zhang X, Liu EQ, Broders H. 2011. Strain and Sex Differences in Anxiety-Like and Social Behaviors in C57BL/6J and BALB/cJ Mice. Exp Anim Tokyo,60(2) 111-123
五、获奖情况
1. 2002年获得陕西省优秀博士论文
2. 2003年获得金沙1005cc登录网址是多少学科建设先进个人
3. 2003年获得金沙1005cc登录网址是多少优秀本科生指导教师
4. 2008 年获得陕西省青年科技奖
5. 2012年获得陕西省优秀学会工作者
6. 2014年获得陕西省高等学校科学技术一等奖
7. 2016年获得陕西省科学技术二等奖
8. 2016年获得陕西省优秀博士论文指导教师
